Jarrow Formulas SAM-e 400 provides a full 400mg SAM-e (net yield) from 800mg of SAM-e tosylate disulfate. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.
Contains more of the active S,S form.
Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e, the highest active level available.
SAM-e has been clinically shown to have the following benefits:
Joint strength.
SAM-e supports the production of healthy connective tissue through transsulfuration. In this process, critical components of connective tissue, known as glycosaminoglycans (GAGs), including glucosamine and chondroitin, are sulfated by SAM-e metabolites to yield sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
Brain metabolism.
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).
Liver.
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function, including phase II detoxification.
Jarrow formulas SAM-e 400 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.
Full potency 400mg SAM-e (net yield) is derived from 800mg of SAM-e tosylate disulfate.
Store in a cool, dry place.

TESTED TO BE TRUSTED

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Ingredients: Cellulose, Glyceryl Behenate, Magnesium Stearate (Vegetable Source), Silicon Dioxide, Mannitol, Sodium Starch Glycolate and an Enteric Coating(Methacrylate Copolymers, Magnesium Silicate, Titanium Dioxide, Triethyl Citrate, Silicon Dioxide and Riboflavin). No Wheat, No Gluten, No Soybeans, No Dairy, No Egg, No Fish/Shellfish, No Peanuts/Tree Nuts. Suitable For Vegetarians/Vegans.

Take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional.

Individuals using prescribed medications such as antidepressants, including selective serotonin re-uptake inhibitors (SSRIs) and MAO inhibitors should consult a physician before using. Individuals with Parkinson's disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended intake. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use. Do not use if outer seal of blister pack is broken. Full potency 400mg SAM-e (net yield) is derived from 800mg of SAM-e tosylate disulfate. Store in a cool, dry place.